Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Plasma cell myelomas
ADR ID BADD_A06747
ADR Hierarchy
01      Blood and lymphatic system disorders
01.14      Plasma cell neoplasms
01.14.02      Plasma cell myelomas
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.23      Plasma cell neoplasms
16.23.02      Plasma cell myelomas
Description A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. [MeSH]
MedDRA Code 10074470
MeSH ID D009101
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Multiple Myeloma | Multiple Myelomas | Myelomas, Multiple | Myeloma, Multiple | Myeloma, Plasma-Cell | Myeloma, Plasma Cell | Myelomas, Plasma-Cell | Plasma-Cell Myeloma | Plasma-Cell Myelomas | Myelomatosis | Myelomatoses | Plasma Cell Myeloma | Cell Myeloma, Plasma | Cell Myelomas, Plasma | Myelomas, Plasma Cell | Plasma Cell Myelomas | Kahler Disease | Disease, Kahler | Myeloma-Multiple | Myeloma Multiple | Myeloma-Multiples
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug Name
BADD_D01223Ixazomib
BADD_D01250Lasofoxifene
BADD_D01251Latanoprost
BADD_D01253Lenalidomide
BADD_D01300Lisinopril
BADD_D01322Losartan
BADD_D01376Melphalan
BADD_D01418Methotrexate
BADD_D01506Muromonab-cd3
BADD_D01507Mycophenolate mofetil
BADD_D01567Nilotinib
BADD_D01629Osimertinib
BADD_D01645Oxycodone
BADD_D01662Pamidronic acid
BADD_D01668Pantoprazole
BADD_D01676Paricalcitol
BADD_D01777Pioglitazone
BADD_D01783Pirfenidone
BADD_D01798Pomalidomide
BADD_D01817Pramipexole
BADD_D01818Pramipexole dihydrochloride
BADD_D01834Prednisone
BADD_D01835Pregabalin
BADD_D01858Propagermanium
BADD_D01903Raloxifene
BADD_D01908Ramelteon
BADD_D01948Riociguat
BADD_D01954Rivaroxaban
BADD_D01978Ruxolitinib
BADD_D02007Semaxanib
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